Precautions: Sodium monofluoroacetate is toxic to all warm-blooded animals. Sodium monofluoroacetate poisoning results from fluoroacetate changing into fluoroacetate within cell mitochondria. Poisoning is characterized by a symptom-free period of 0.5 to 2 hours or longer between ingestion and onset of symptoms (nausea, vomiting, diarrhea, and hyperactive behaviour leading to convulsions). In monkeys, and presumably in humans, effects on the heart are the primary cause of death. The first symptoms of poisoning are changes of heart sounds and premature, weak contractions. No effective antidote is known.
Compound 1080 is highly toxic to warm blooded animals, including man, when taken internally. Compound 1080 is hazardous to domestic animals including livestock and pets. Dogs are particularly susceptible. In field studies, dogs have died after they attacked collared livestock and punctured the collars. As little as 0.1 ml of a LP collar’s contents may be fatal to a 25 pound dog. Dogs could be poisoned by scavenging the carcasses of collared livestock. Therefore, to minimize the potential hazard to dogs, promptly dispose of all livestock carcasses as well as coyote carcasses suspected of being poisoned by Compound 1080 according to instructions in this bulletin.